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Imagine four leading academic centres of excellence in genomics, proteomics, biotechnology and bioinformatics within Euregio Meuse-Rhine. Imagine in each centre an innovative offer of high-quality services to companies and research institutes, through core facilities exploiting state-of-the-art science and technology. Imagine that the centres are linked via a powerful computer grid equipped with a high-performance Laboratory Information Management System and that this secured system guarantees confidentiality while offering clients easy access to the “virtual lab”. Imagine that this innovative community provides active coaching in bioinformatics and in “virtual lab” management. Imagine that you can access the “virtual lab” where expertise, equipment, and resources are perfectly balanced. This, in a nutshell, is what alma-grid is all about.